Transcription factor interplay during Drosophila haematopoiesis
نویسندگان
چکیده
منابع مشابه
Transcription factor networks in Drosophila melanogaster.
Specific cellular fates and functions depend on differential gene expression, which occurs primarily at the transcriptional level and is controlled by complex regulatory networks of transcription factors (TFs). TFs act through combinatorial interactions with other TFs, cofactors, and chromatin-remodeling proteins. Here, we define protein-protein interactions using a coaffinity purification/mass...
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The genetic mechanisms controlling organ shape are largely unknown. We show that the Drosophila grain gene is required during development for shaping the adult legs and the larval posterior spiracles. Mutant legs are short and wide rather than long and thin, while the spiracles are flat instead of dome-shaped. We demonstrate that grain encodes the GATAc transcription factor. Analysis of loss-of...
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ژورنال
عنوان ژورنال: The International Journal of Developmental Biology
سال: 2010
ISSN: 0214-6282
DOI: 10.1387/ijdb.093054lw